Sta. Maria is situated in the middle of the Val Müstair. From here the Umbrail pass road, which is only open in summer, leads over to the Italian Valtellina and the Stelvio Pass. Centrally located, Sta. Maria offers an abundance of hotels, gastronomic offers and shops. In addition to the campsite Pè da Munt, visitors will also find a youth hostel here. In the district of Sielva there is also the hospital (Ospidal) of the valley with pharmacy. Attractions are the hand weaving mill Tessanda, the mill Mall, the museum 14/18 as well as the "smallest whisky bar on earth" with attached Whisky Museum and HighGlen Whisky Distillery. In summer Sta. Maria is the starting point for numerous hiking and biking tours. In winter, the free sports bus and the hourly post bus make it easy to reach the whole winter offer in a short time and many winter walks, snowshoe and ski tours can be undertaken directly from Sta. Maria.